Inspired by their patients seeking healthier looking skin, SkinMedica® was founded by pioneers in the science of skin rejuvenation. Our co-founder, the renowned dermatologist Dr. Richard Fitzpatrick, had a vision to develop a better way to slow the aging process and unlock the potential of the skin to heal from within; and in 1999, the groundbreaking scientifically based skin care line called SkinMedica® was born.


What is the GRASS Regime?

Skin Medica recommends a GRASS Regimen to achieve your most optimal skin health. GRASS Regimen is an acronym to help patients identify what products they need. It stands for Growth Factors, Retinols, Antioxidants, Specialty Products that are customizable to your specific needs, and SPF, which is the most important skin component to any skin regimen. With this prescribed and individualized regimen Skin Medica was able to make the science of beauty a reality. A GRASS Regimen is only from SkinMedica and has been clinically proven, in fact in clinical trials 100% of patients that used a GRASS Regimen saw improvements in fine lines, wrinkles, skin brightness, and texture of their skin.

How Do I Choose the Correct Products?

In each category there is a product that you can use specifically within the GRASS Regimen. Choose one from each category to formulate your customized skin care regime. The specialty category is the exception! If you have fine lines and wrinkles around your eyes choose TNS Eye Repair. If you have dark spots on your skin choose LYTERA to even skin tone and radiance. If you would like your lips smoother and plumper choose TNS Lip Plump System. If you have redness of your skin, choose Redness Relief CalmPlex. Or choose all four if needed!

TNS Essential Serum®

What is special about this product?

TNS Essential Serum® offers an unprecedented combination of the renowned growth factor formula, TNS Recovery Complex® in one chamber and APS Corrective Complex™ in the other.

TNS® is the main ingredient in TNS Recovery Complex’s patented skin treatment which is formulated from naturally occurring growth factors, antioxidants, soluble collagen, cytokines and matrix proteins (93.6% concentration).

Clinical studies with TNS Recovery Complex® have shown:

  • Reduced appearance of fine lines and wrinkles
  • Enhanced skin texture and tone

APS Corrective Complex™ is a formulation of antioxidants, peptides and other innovative ingredients that in combination improve the overall appearance of skin.

APS Corrective Complex™:

  • Helps to smooth skin
  • Helps fight free radical damage
  • Minimizes the appearance of skin discoloration

TNS Essential Serum® should be applied after cleansing and toning the skin and prior to applying any other products, including sunscreens.

You should use TNS Essential Serum® as long as you wish to improve the overall appearance of your skin. Our clinical studies show that initial results occur in 30 days with optimal results occurring in 90 days. For best results, you should use twice daily.

HA5 Rejuvenating Hydrator

What’s the difference between a moisturizer and a hydrator?

A moisturizer is a cosmetic cream or lotion made with humectants or occlusive or a combination of both that prevents skin dryness. A hydrator is a cosmetic treatment product that promotes epidermal health by supporting the skin’s natural ability to replenish HA. SCE stands for stem cell extract. VitisenSCE™ technology contains a proprietary antioxidant extracted from Vitis vinifera flower stem cells. Exclusive to SkinMedica®, it is one of the key ingredients that allows HAs to support the skin’s ability to replenish its own hyaluronic acid for overall skin health. The whey protein used in HA5® is derived from milk powder. Therefore a person with a history of milk or whey protein that triggers an immune response should not use this product. HA5® Rejuvenating Hydrator should be applied twice daily – in the morning and evening-immediately before moisturizer in a normal regimen.

Retinol Complex

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Wrinkles are simply creases in the skin that occur when collagen and elastin break down over time due to age, use, UV exposure and smoking. Collagen and elastin are connective tissue found within your skin.  As these two are weakened, your skin loses strength and flexibility…And once that happens, skin begins to sag thus causing wrinkles to form. While some of this process is natural and determined by genetics and age, it is possible to delay this effect quite a while if you follow a few steps.

Decades of clinical studies show that retinol is a miracle ingredient when it comes to the skin. Retinol

  • stimulates the production of collagen and elastin
  • increases cell turnover
  • fades pigmentation
  • shrinks pores
  • retexturizes the skin leading to reduction in fine lines and smooth skin surface.

Retinol is photosensitive and should only be worn at night. Never go outside or into the sunlight with it on; this could cause adverse effects. You could begin to notice changes anywhere from within a week to about eight weeks.

Retinoids exfoliates your skin and may cause it to become sensitive. It may peel, flake, turn red and become dry during initial use. It is key to use small amounts every other day, until your skin works up tolerance for vitamin-A.” Wash with a gentle face scrub a few times a week to clear the top layer of old skin.

People with rosacea or eczema should not use Retinol. It should not be used with a heavy hand and should be used [in tandem] with a moisturizer.


Sunscreen is an essential component of any skin care regime. Sunscreen protects the skin from the sun’s damaging UVA and UVB rays which cause fine lines and wrinkles and sun spots.

Lytera Skin Brightening Complex®

Lytera® is a novel, non-prescription, non-hydroquinone skin brightening product that minimizes the appearance of fine lines and wrinkles. Clinical studies with Lytera® have shown:

  • Improved evenness of skin tone
  • Improved overall appearance of the skin
  • Increased radiance and clarity of the skin
  • Lessened appearance of darker patches and discolorations

Lytera® is designed to improve clarity, evenness and overall appearance of the skin.

Lytera® can be used on the face, neck, chest or other affected areas.

In clinical studies, the side effects associated with Lytera® were mild and included redness, tingling and dryness. A temporary warm, tingling sensation may occur immediately after application.

In clinical studies, improvements were seen in as early as 4 weeks. For best results, use sunscreen daily and avoid sun exposure.

We do not recommend using Lytera® while pregnant, lactating or planning on becoming pregnant.

TNS Lip Plump System®

TNS Lip Renewal® contains TNS and peptides to help improve the appearance of the lip area and hyaluronic filling spheres to smooth the appearance of fine lines in the lip area. TNS is a mixture of human growth factors, cytokines, antioxidants and matrix proteins. TNS Lip Plump System® should be applied as needed to moisturize and help plump the lips throughout the day.

TNS Eye Repair®

This product contains TNS® as well as vitamins C and E to improve the overall appearance of the skin under your eyes.

TNS Eye Repair is formulated to help reduce the appearance of fine lines and wrinkles while hydrating the skin around the eyes.

TNS Eye Repair® should be applied twice daily, morning and evening, after applying treatment products.

Using a spatula, apply a thin layer with your finger tip to the skin.

Apply to the skin underneath the eyes and around the outside corners of the eye area. Avoid the eyelids.

Redness Relief ComPlex
Facial Cleanser 6 fl. oz.

Our cleansers remove dirt, makeup, and environmental pollutants leaving your skin feeling refreshed and ready for treatments.

Rejuvenative Toner 6 fl. oz.

Our toner is designed to cleanse the skin and shrink the appearance of pores.

General Information

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There are SkinMedica® products that are formulated to be used on all skin types and most skin conditions including sensitive and post-procedure skin. We recommend you always ask your physician which products and regimen will best address your skin type and concerns.

Photodamage to the skin is caused by exposure to harmful ultraviolet light. Photodamage can be acute, as in sunburn, or more commonly, chronic, due to gradual changes in the skin caused by an accumulation of sun exposure throughout one’s life. Sun exposure is by far the most influential environmental factor affecting aging of the skin.

Lines and wrinkles are caused by degenerative changes in the proteins of the skin’s infrastructure such as loss of stored antioxidants and reduction in collagen. Wrinkles are also caused by movement of the skin resulting in creases over time.

Age spots are also known as sun spots or solar lentigines. Age spots are associated with cumulative sun exposure. Sun spots mostly appear in areas consistently exposed to sunlight such as the back of the hands, the forearms, neck, chest and face. The pigment producing cells in the skin (melanocytes) are stimulated to produce more pigment when exposed to ultraviolet rays.

Using sun protection and appropriate skin care products containing specialty ingredients is essential in maintaining healthy skin.

We have not done any product testing on pregnant women or nursing mothers. We recommend you consult your physician before using any SkinMedica® products during pregnancy or while breast feeding.

SkinMedica® does not conduct product testing on animals.